The Netherlands Bioinformatics Centre (NBIC) is the Dutch network of bioinformatics experts active in research, education and support. Over 100 bioinformatics scientists, including 40 ‘NBIC faculty’ members, structurally collaborate in a networked, supra-institutional organisation. The strong Dutch research community establishes the best teachers’ base for a broad and lively NBIC bioinformatics training programme. In dedicated teams, a contingent of over 50 programmers and software engineers develops re-usable solutions and guides the professional implementation of novel software and databases. Where necessary, access to high end computing and e-science infrastructures is arranged through collaboration with partner organisations.