Bioinformatics - a user's approach

General info

Date 

30 Aug 2010 - 03 Sep 2010 

Location

Wageningen University, The Netherlands

Website

http://www.graduateschool-eps.info/index.php?optio...

Organiser

The interuniversity Graduate School 'Experimental Plant Sciences' (EPS)

Teacher(s)

Leunissen, Jack Prof. dr.

Contact(s)

Ria Fonteyn

Description

Aim: The aim of this course is to present a hands-on approach to bioinformatics utility software for computing novices. The course will provide an overview of available software, discuss some of the ideas behind he approaches and tackle some common tasks.

Content: There will be a mixture of lectures and frequent practical sessions. The course has many practical examples which try to follow typical mini projects so that the relevance is apparent. Topics that will be adressed during the morning and afternoon sessions include accessing, searching and retrieval information from various Internet Data Resources (e.g. non-sequence databases, the Genome Database, clinical databases, sequence databases, etc.); Sequence analysis and alignment (e.g. BLAST, dotplot, ORF identification and translation. restriction maps; primer design, etc.); Advanced sequence analysis (e.g. scoring matrices, genetic code scoring, chemical similarity, observed substitutions, etc.); Database mining (e.g. BLAST, FASTA, BLITZ, etc); Gene, identification (e.g. Genscan, etc.), prediction and annotation, as well as Computational protein analysis (e.g. proteins sequence analysis, paralogous and othologous sequences, primary and secondary structure, sequence motifs and domains, multiple sequence alignments, tertiary and quaternary structure, etc).