Applied genomics of industrial fermentation

General info

Date 

11 Oct 2010 - 15 Oct 2010 

Location

Conference Centre ‘De Wageningse Berg’ Generaal Foulkesweg 96 6703 DS Wageningen The Netherlands

Website

http://www.bsdl-edu.bt.tudelft.nl

Keywords

genomics, fermentation, Genome (sequencing and annotation), Molecular cell biology, Transcriptomics technology and Proteomics technology

Organiser

BDSL / TU Delft / Kluyver / VLAG

Contact(s)

Ger Aggenbach

Description

The Advanced Course on “Applied Genomics of Industrial Fermentation” aims at familiarizing industrial and academic research professionals (i.e. MSc, PhD) with the modern concepts of Genomics, their use in microbial research and development, and their utility in contemporary biotechnological industry. The Course is organised through the Kluyver Centre for Genomics of Industrial Fermentation (described on the back of this brochure), and is instrumental in the dissemination of the results of this Centre of Excellence.

Applied Genomics is defined as the singular and combined utilization of the modern molecular research tools transcriptomics, proteomics, and metabolomics to elucidate cellular regulatory mechanisms of sensing and signalling, metabolic flux and physiology. Mathematical tools are indispensable to analyze, interpret and model the experimental data. In combined approaches, these tools offer unprecedented possibilities for industrial fermentation research.

Experts will present lectures on genome analysis and -interpretation, genome-wide gene expression analysis (DNA micro arrays, transcriptomics), whole-organism protein expression and activity analysis (proteomics), and metabolic pathway analysis (metabolomics). Data handling and bioinformatics are key to the successful application of Applied Genomics and hence, will be an integral part of the course. Application of these technologies in industrial R&D (modelling, network analysis and metabolic engineering) will be illustrated with real-life examples. The necessary links between theory and practice will be provided in interactive case studies and demo-workshops. In addition, there will be ample opportunity to interact and discuss with the expert lecturers in several small-group, round-table discussions.