New tool: GO-Elite

16 Aug 2012

Alexander Zambon (UC San Diego) and colleagues, including NBIC Faculty member Chris Evelo, have developed a new tool to perform over-representation analysis on structured ontology annotations, pathway databases or biological IDs. Numerous over-representation tools are already available, but many of these are limited in scope, lack interchangeability or quickly become outdated because they are linked to only one resource. GO-Elite provides users with a flexible pathway analysis tool that uses the relationships between pathways, ontology species and gene ID systems to generate a minimally non-redundant set of results. Results from GO-Elite can be visualized on WikiPathways or as networks. GO-Elite is available as a web interface, GenMAPP-CS plugin and cross-platform application.

Zambon AC, Gaj S, Ho I, Hanspers K, Vranizan K, Evelo CT, Conklin BR, Pico AR and Salomonis N
GO-Elite: a flexible solution for pathway and ontology over-representation
Bioinformatics 2012 28(16):2209-2210

For more bioinformatics tools, please check the NBIC tools list.

By: Esther Thole

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