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The co-evolution of the receptor signalling network of natural killer cells with its ligands

General info

Date from - to
01 Jun 2009

Abstract

Natural killer cells play an important role in the immune system. These cells recognise infected cells using their external inhibiting and activating receptors. Next to gaining more insight in the network of receptors and their ligands, the research will also study how the system develops (co-evolution) in relation to the evolution of pathogens. Ultimately, a mathematical model will clarify the role of the activating receptors.

Coordinator: Prof. R.J. de Boer (Utrecht University)

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