MCSIS heterogeneous data handling
General info
- Date from - to
- 01 Sep 2007 - 01 Sep 2011
- Project leader(s)
- Vriend, Gert Prof. dr.
Abstract
The MCSIS (Molecular Class Specific Information System) technology deals with heterogeneous data that are available for G protein-coupled receptors, as well as for nuclear hormone receptors. It extracts data from many large, normally monolithic, databases, and combines these in one information system. In this project the MCSIS software is automated so that bioscientists can make their own MCSIS for the molecule of their own interest. Recently developed software products are integrated and we work to GRID-enable the MCSIS technology.
Publications
- Correlated mutation analyses on super-family alignments reveal functionally important residues
- GPCRDB information system for G protein-coupled receptors
- Structure and function of 2,3-dimethylmalate lyase, a PEP mutase/isocitrate lyase superfamily member
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