Hoen, 't Peter-Bram Dr.
General info
- p.a.c.hoen@removethis.Lumc.nl
- Phone number(s)
- +31 71 526 9421
- Fax
- +31 71 526 8285
- Website(s)
- http://www.biosemantics.org/in...
Principal Research
Peter Bram 't Hoen is working as assistant professor for the Center for Human and Clinical Genetics (LUMC), and is responsible for all bioinformatics activities in the Department of Human Genetics. He is the direct supervisor of 3 post-doctoral researchers, 4 Ph.D. students, 2 scientific programmers, and 3 technicians.
Over the past few years, he has been at the forefront of the development and application of new high-throughput techniques such as microarrays, high-throughput sequencing and mass spectrometry-based proteomics. Although he was trained as a molecular biologist, he acquired bioinformatics and programming skills and has become proficient in data analysis, data integration and statistics over the past few years. His main incentive is to make optimal use of available data to improve understanding of biology in general and muscle biology in particular, and to translate this into clinically relevant applications. Biosemantics methods are the core technology used for data interpretation and data integration. He leads a multidisciplinary team of researchers (bioinformaticians, biostatisticians, molecular biologists, biochemists). They focus on the regulation of gene expression, miRNA biology, (cross-species) integration of –omics data, analysis of biological networks, antisense and RNAi technology, statistical methods for next generation sequencing data analysis, protein biomarker discovery.