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Projects

From spiking neurons to brain waves

15 Oct 2008- 31 Mar 2013 

In this research project we will test three hypotheses. The first hypothesis is related to the functional role of neuronal oscillations in the gamma-f…

Microbial ecosystems and multiple environment stoichiometric analyses

1 Nov 2008-  1 Oct 2011 

The attainable flux states of a metabolic network of an organism result from selective pressures acting on the organism's ability to cope with: (i) ch…

Modeling gene networks in synaptic computation: A Bayesian pertubation approach

1 Nov 2008- 31 Oct 2012 

The synapse is the basic unit of computation in the brain. Its ability to adapt its strength on a millisecond timescale is a prerequisite for informat…

Multi-scale modelling of calcification in scleratinin corals

1 Jun 2009 

In most cases, form and structure of corals are determined on the micro-level ? the classical method. In this project, the research will focus on gene…

Neuronal Netwerk Formation through Reciprocal Interacties between Activity and Structure

1 Dec 2008- 12 Jan 2011 

Information processing in the brain is based on the dynamics of electrical activity in large neuronal networks. Activity dynamics depends on network s…

Reverse physiology of the cortical microcircuit

1 Jun 2009 

This project focuses on the way in which a single neuron (nerve cell) involves cells in its direct environment in distributing collected information. …

The co-evolution of the receptor signalling network of natural killer cells with its ligands

1 Jun 2009 

Natural killer cells play an important role in the immune system. These cells recognise infected cells using their external inhibiting and activating …

The evolution of stochastic heterogeneous networks as bet-hedging adaptations to fluctuating environments

1 Jun 2009 

In the single-celled organism Bacillus subtilis, the formation process of spores can adapt to extreme circumstances. However, even though all cells ar…

The regulatory network underlying malaria parasite-host interactions

1 Jun 2009 

In the life cycle of the malaria parasite, entering a red blood cell is a crucial step. The parasite can employ different mechanisms to enter, dependi…

Understanding hierarchical and metabolic regulation of metabolic networks through Bayesian constraint modelling

1 Dec 2008-  1 Dec 2012 

Integration of datasets for understanding the interplay between the various levels of cellular organization is an important aspect of today's (systems…